The Edward Mallinckrodt, Jr. Foundation supports early-stage biomedical investigators engaged in basic and translational research that has the potential to make fundamental advances in biomedical science. The funds are designed to provide to tenure track faculty members in their first to fourth year, at American Institutions, who hold M.D. and/or Ph.D. degrees, start-up support to move the project forward to the point where NIH R01 or other independent funding can be obtained. Applicants with current R01 funding should not apply.